Apoptosis Reagents and Kits
Abcam Human TNFRSF1A (TNF Receptor I) knockout HeLa cell lysate.
Human TNFRSF1A (TNF Receptor I) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human ABCC2 knockout A549 cell lysate.
Human ABCC2 knockout A549 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
American Research Products Inc Rat Factor related Apoptosis l
Rat Factor-related Apoptosis ligand FASL ELISA Kit from CUSABIO Detection Range 31 25 pg/mL-2000 pg/mL Sensitivity 7 8 pg/mL Sample serum plasma tissue homogenates Method Sandwich
Eurofins Discoverx KILR U2OS (Human) EGFR Cytotoxicity Assay Kit (Clone)
The KILR Human EGFR Stable Cell Line Cytotoxicity Assay (U2OS) utilizes the stable, engineered U2OS-EGFR target cell line for quantifying effector-induced cell death. This assay enables measurement of immune cell-mediated killing through ADCC, ADCP and CDC. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Abcam Human CASP1 (Caspase-1) knockout THP-1 cell lysate.
Human CASP1 (Caspase-1) knockout THP-1 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human PVR (Poliovirus Receptor) knockout A549 cell lysate.
Human PVR (Poliovirus Receptor) knockout A549 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Selleck Chemical LLC RK-33 5mg 1070773-09-9
RK-33 is a first-in-class small molecule inhibitor of DDX3 (a RNA helicase) and causes G1 cell cycle arrest, induces apoptosis, and promotes radiation sensitization in DDX3-overexpressing cells. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Abcam Human IKBKB (IKK beta) knockout HeLa cell lysate.
Human IKBKB (IKK beta) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Enzo Life Sciences Z-WEHD-FMK (Ready-to-Use) (20µl)
Inhibitor of caspase-1, -4, -5 and -14. Irreversible, cell permeable inhibitor of caspase-1 and -5. Inhibits also caspase-4 and-14. Designed as a methyl ester to facilitate cell permeability. Alternative name: Caspase 1 inhibitor (fluoromethylketone), Caspase 5 inhibitor (fluoromethylketone). Formula: C37H42FN7O11. MW: 763.8. Purity: ≥99% (HPLC). Formulation: Liquid. In DMSO. Long Term Storage: -20°C.
Apexbio Technology LLC Caspase-3/7 Inhibitor I 220509-74-0 5mg
Caspase-3/7 Inhibitor I (CAS 220509-74-0) is a reversible inhibitor of caspase-3 and caspase-7 structurally belonging to the isatin sulfonamide class It exhibits selective inhibition toward caspase-3 and caspase-7 with Ki values of 60 nM and 170 nM respectively while minimally affecting caspase-9 (Ki 3 1 mM) and showing negligible activity against other caspases (caspases 1 2 4 6 and 8 Ki 25 mM) In cell-based assays this inhibitor effectively reduces apoptosis induced by camptothecin in Jurkat cells (IC50 50 M) and markedly suppresses apoptosis in chondrocytes at similar concentrations The compound is routinely utilized in apoptosis research and may offer therapeutic insights into apoptotic modulation
Abcam Human POR (Cytochrome P450 Reductase) knockout HCT116 cell lysate.
Human POR (Cytochrome P450 Reductase) knockout HCT116 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human ROCK2 knockout HeLa cell lysate.
Human ROCK2 knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human PMS2 knockout HeLa cell lysate.
Human PMS2 knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
AdipoGen WP1130
Chemical. CAS 856243-80-6. Formula C19H18BrN3O. MW 384.3. WP1130 is a second-generation tyrphostin derivative initially identified as a JAK2 signaling inhibitor through JAK2 ubiquitination that reduces STAT activation stimulated by cytokines such as IL-6 and IL-3 through the rapid down-regulation of upstream JAK kinases. WP1130 has also been identified as a partially selective cell permeable deubiquitinating enzyme/deubiquitinase DUB inhibitor that directly inhibits DUB activity of USP9x, USP5, USP14, USP24, UCH37, UCHL1 and UCHL5, leading to rapid accumulation of polyubiquitinated K48/K63-linked proteins into juxtanuclear aggresomes and tumor cell apoptosis, accounting for its anti-cancer properties. Through this mechanism, WP1130 has been shown to downregulate the antiapoptotic proteins Bcr/Abl and Jak2 and to upregulate the proapoptotic proteins MCL-1 and p53.
Cayman Chemical Z-VAD-AMC (acetate), Purity: ≥95%, 5 mg
A caspase-1 fluorogenic substrate; upon enzymatic cleavage, AMC is released and its fluorescence can be used to quantify enzyme activity; ex/em = 340-360/440-460 nm, respectively